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This tutorial highlights the ability of the iQue Screener PLUS to expand the envelope of true immunology screening by combining immunophenotyping, cell health, cell function, and cytokine profiling into single high content assays for immuno-oncology, immune targets, and antibody screening applications.
Author: Joseph Zock
Rodent cytokine quantification using QBeads on iQue Screener offer three important benefits for screening: multiplexed no-wash protocols, compatibility with a high degree of assay miniaturization, and rapid plate sampling speeds.
"Tumor-promoting PRL-3 is suggested as a therapeutic target in cancer cells. Thus, finding inhibitors would be highly desirable. Presented here are findings from studying PRL-3 in epithelial 3D cell culture models and the challenging endeavors of inhibitor development for PRL-3."
Author: Prof. Dr. Maja Köhn
The findings from this trial highlight the multiplicity of mutation-based pathologies and pinpoint novel precision-based therapeutic strategies to pursue for intrahepatic cholangiocarcinoma, and potentially, in future basket trials of diverse tumors using a similar stratification approach.
Author: Assoc. Prof. Dr. Jesper Bøje Andersen