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Related topics: Oncology, Antibody Discovery, Filtration, Sample Preparation


Impact of the Claristep® Filtration System on Recovery and Adsorption of Various Therapeutic Proteins at Low Sample Volumes

We have tested the novel filter device Claristep® for the preparation of protein samples containing four different therapeutic proteins by using RP and SEC HPLC. We observed no significantly reduction of the product concentration at 1 mg/mL and an insignificant binding of ~4.0 µg mAb per filter.

Author: Alexander Croon, Johannes Felix Buyel

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