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Related topics: Oncology, Oncology General


PRL-3 phosphatase: Roles and targeting in cancer - Lecture Research Xchange Forum 2017

"Tumor-promoting PRL-3 is suggested as a therapeutic target in cancer cells. Thus, finding inhibitors would be highly desirable. Presented here are findings from studying PRL-3 in epithelial 3D cell culture models and the challenging endeavors of inhibitor development for PRL-3."

Author: Prof. Dr. Maja Köhn

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Related topics: Oncology, Immuno-Oncology, Small Molecule Drug Discovery, Cell Analytics


High Throughput Flow - Enabling Multiplexed, Miniaturized, High Throughput Cell-and Bead-Based Assays

Flow cytometry is an attractive technique for suspension based assays – learn how IntelliCyt has further optimized this technology to facilitate a broad range of cell health profiling assays on physiologically relevant samples.

Author: Steve Davenport, Robbie Narang

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Related topics: Antibody Discovery, Cell Analytics


Multiplexed Screening for Antibody Production

A Novel Multiplexed Screening Assay for Assessing Productivity of Antibody-Secreting Cell Lines: Simultaneous Measurement of Secreted Protein and Viable Cell Count

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Related topics: Oncology, Oncology General


Genomic Perturbations Reveal Distinct Regulatory Networks in Intrahepatic Cholangiocarcinoma - Lecture Research Xchange Forum 2017

The findings from this trial highlight the multiplicity of mutation-based pathologies and pinpoint novel precision-based therapeutic strategies to pursue for intrahepatic cholangiocarcinoma, and potentially, in future basket trials of diverse tumors using a similar stratification approach.

Author: Assoc. Prof. Dr. Jesper Bøje Andersen

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Related topics: Oncology, Oncology General


The p53-Mdm2 system modifies chromatin and DNA replication - Lecture Research Xchange Forum 2017

New discoveries in p53 research elucidate that the p53-Mdm2 system provides means to maintain DNA integrity and chromatin stability. These novel activities provide potential targets and opportunities for selectively interfering with tumor cell proliferation.

Author: Prof. Dr. med. Matthias Dobbelstein

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