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Brief review summing up the limits of target-based approaches and the advantages of next generation phenotypic screening technologies in the large scale industrial discovery of first-in-class small-molecule drugs.
Quick and convenient determination of apoptotic processes by simultaneous detection of four well-established apoptosis markers in a single validated and easy-to-use multiplex assay.
Author: Robbie Narang, Zhaoping Liu, Kim Luu
MultiCyt 4-Plex Apoptosis Screening Kit
Presentation of successful identification of small molecules with immunoregulatory capacity by well-established phenotypic screening methods using multiplexed, no wash, high throughput flow cytometer readouts.
Author: Stefan Frischbutter, Olga Trupp, Anja Schaus, Van Duc Dang, Imme Sakwa, Simon Fillatreau, Alf Hamann